Mutant Characteristics

The table below shows amino acid substitutions in the NAs of variants in clinical samples or isolates causing reduced antiviral susceptibility.

Differential susceptibility of mutants, e.g. H274Y and Q136K, to the antivirals, especially oseltamivir and zanamivir, reflects the complementary activities of the antivirals against viruses with certain mutations.

Table of amino acid substitutions adobe pdf icon2